Jan. 24, 2013 ? Here's a wake-up call for snorers: Snoring may put you at a greater risk than those who are overweight, smoke or have high cholesterol to have thickening or abnormalities in the carotid artery, according to researchers at Henry Ford Hospital in Detroit.
The increased thickening in the lining of the two large blood vessels that supply the brain with oxygenated blood is a precursor to atherosclerosis, a hardening of the arteries responsible for many vascular diseases.
"Snoring is more than a bedtime annoyance and it shouldn't be ignored. Patients need to seek treatment in the same way they would if they had sleep apnea, high blood pressure or other risk factors for cardiovascular disease," says lead study author Robert Deeb, M.D., with the Department of Otolaryngology-Head & Neck Surgery at Henry Ford.
"Our study adds to the growing body of evidence suggesting that isolated snoring may not be as benign as first suspected. So instead of kicking your snoring bed partner out of the room or spending sleepless nights elbowing him or her, seek out medical treatment for the snorer."
The study reveals changes in the carotid artery with snorers -- even for those without sleep apnea -- likely due to the trauma and subsequent inflammation caused by the vibrations of snoring.
Study results will be presented January 25 at the 2013 Combined Sections Meeting of the Triological Society in Scottsdale, Ariz. It has been submitted to The Laryngoscope journal for publication.
Obstructive sleep apnea (OSA) -- a sleep disorder that occurs due to the collapse of the airway in the throat during sleep and causes loud snoring and periodic pauses in breathing -- has long been linked to cardiovascular disease, along with a host of other serious health issues.
But the risk for cardiovascular disease may actually begin with snoring, long before it becomes OSA. Until now, there was little evidence in humans to show a similar connection between snoring and cardiovascular risk.
For the Henry Ford study, Dr. Deeb and senior study author Kathleen Yaremchuk, M.D., reviewed data for 913 patients who had been evaluated by the institution's sleep center.
Patients, ages 18-50, who had participated in a diagnostic sleep study between December 2006 and January 2012 were included in the study. None of the participants had sleep apnea.
In all, 54 patients completed the snore outcomes survey regarding their snoring habits, as well as underwent a carotid artery duplex ultrasound to measure the intima-media thickness of the carotid arteries.
Carotid intima-media thickness, a measurement of the thickness of the innermost two layers of the arterial wall, may be used to detect the presence and to track the progression of atherosclerotic disease. Intima-media thickness is the first sign of carotid artery disease.
Compared to non-snorers, snorers were found to have a significantly greater intima-media thickness of the carotid arteries, the study finds.
The study also revealed no statistically significant differences in intima-media thickness for patients with or without some of the traditional risk factors for cardiovascular disease -- smoking, diabetes, hypertension or hypercholesterolemia.
"Snoring is generally regarded as a cosmetic issue by health insurance, requiring significant out-of-pocket expenses by patients. We're hoping to change that thinking so patients can get the early treatment they need, before more serious health issues arise."
The Henry Ford research team plans to conduct another long-term study on this topic, particularly to determine if there's an increased incidence of cardiovascular events in patients who snore.
Along with Drs. Deeb and Yaremchuk, Henry Ford study co-authors are Paul Judge, M.D.; Ed Peterson, Ph.D.; and Judith C. Lin, M.D.
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The Equipment Leasing and Finance Association, which represents the $725 billion equipment finance sector, has issued its "Top 10 Equipment Acquisition Trends for 2013."
1.?????? Corporate perceptions of the economic outlook will be a primary driver of business investment decisions.?Despite pressing considerations such as technological innovations and aging equipment, the economy will be the true barometer for whether or not businesses acquire new equipment in 2013.
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2.?????? Equipment investment will pick up in the second half of 2013. Equipment investment will grow this year, although the rate of growth will be hampered by fiscal uncertainty. Some companies will remain cautious about taking on large capital investments even now that important decisions impacting short-term fiscal stability have been made. Equipment acquisition activity will gain momentum through relief from the policy uncertainty that brought the economy to the edge of the fiscal cliff.?An improving housing sector will provide an added boost.
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3.?????? Pent-up demand will spur investment across varied equipment types. Demand for replacement equipment will drive investment in the construction, agriculture and transportation categories in particular, while other equipment types will await the replacement cycle.?However, greater economic improvements will be needed before significant equipment investment expansion takes place.
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4.?????? A continuing low interest rate environment will enable companies to acquire the equipment they need and conserve cash.?The prospect of continued low interest rates at least through 2014 will be an incentive for businesses to acquire equipment through financing and still hold on to their cash for uncertainties. In addition to maintaining cash flow, equipment financing will help businesses preserve capital and improve expense planning in challenging economic conditions.
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5.?????? A majority of U.S. businesses will use some form of financing for equipment acquisition.?In 2013, $742 billion (55 percent) of the projected $1.3 trillion investment in plant, equipment and software investment in the United States will be financed through loans, leases and lines of credit.?Seven out of 10 businesses will use at least one form of financing to acquire equipment.
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6.?????? Business size will impact equipment acquisition.?Size will matter when acquiring equipment in 2013.?Primarily larger businesses anticipate increasing equipment spending over the next 12 months. Small companies? high degree of concern about general economic conditions and less access to credit will temper their equipment acquisition plans.?
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7.?????? The gaining prominence of cloud computing will transform the way businesses pay for IT investments. Along with changes in how companies consume software and hardware, cloud computing will spawn new financing options.?Companies will look to equipment financiers for variable payment structures in the cloud. ?
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8.?????? Credit market conditions will remain favorable for long-term equipment financing. Businesses will generally find an improving credit supply as they consider equipment acquisitions.
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9.?????? The one-year extension of bonus depreciation may provide incentives for businesses to acquire equipment. The continuation of the depreciation bonus will allow businesses to deduct up to 50 percent of the cost of new equipment purchases in 2013.
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10.?? Although the value of lease financing will remain, businesses will begin to adapt their equipment acquisition strategies to comply with long-awaited changes to lease accounting standards.?A new draft of proposed changes to lease accounting standards by the Financial Accounting Standards Board and the International Accounting Standards Board should be announced this year, enabling businesses to begin to evaluate how their balance sheets, earnings and other financials will be affected by equipment financing agreements.
Setting the dark on firePublic release date: 23-Jan-2013 [ | E-mail | Share ]
Contact: Douglas Pierce-Price dpiercep@eso.org 49-893-200-6759 ESO
In space, dense clouds of cosmic gas and dust are the birthplaces of new stars. In visible light, this dust is dark and obscuring, hiding the stars behind it. So much so that, when astronomer William Herschel observed one such cloud in the constellation of Scorpius in 1774, he thought it was a region empty of stars and is said to have exclaimed, "Truly there is a hole in the sky here!" [1]
In order to better understand star formation, astronomers need telescopes that can observe at longer wavelengths, such as the submillimetre range, in which the dark dust grains shine rather than absorb light. APEX, on the Chajnantor Plateau in the Chilean Andes, is the largest single-dish submillimetre-wavelength telescope operating in the southern hemisphere, and is ideal for astronomers studying the birth of stars in this way.
Located in the constellation of Orion (The Hunter), 1500 light-years away from Earth, the Orion Molecular Cloud Complex is the closest region of massive star formation to Earth, and contains a treasury of bright nebulae, dark clouds and young stars. The new image shows just part of this vast complex in visible light, with the APEX observations overlaid in brilliant orange tones that seem to set the dark clouds on fire. Often, the glowing knots from APEX correspond to darker patches in visible light -- the tell-tale sign of a dense cloud of dust that absorbs visible light, but glows at submillimetre wavelengths, and possibly a site of star formation.
The bright patch below of the centre of the image is the nebula NGC 1999. This region -- when seen in visible light -- is what astronomers call a reflection nebula, where the pale blue glow of background starlight is reflected from clouds of dust. The nebula is mainly illuminated by the energetic radiation from the young star V380 Orionis [2] lurking at its heart. In the centre of the nebula is a dark patch, which can be seen even more clearly in a well-known image (http://www.spacetelescope.org/images/opo0010a/) from the NASA/ESA Hubble Space Telescope.
Normally, a dark patch such as this would indicate a dense cloud of cosmic dust, obscuring the stars and nebula behind it. However, in this image we can see that the patch remains strikingly dark, even when the APEX observations are included. Thanks to these APEX observations, combined with infrared observations from other telescopes, astronomers believe that the patch is in fact a hole or cavity in the nebula, excavated by material flowing out of the star V380 Orionis. For once, it truly is a hole in the sky!
The region in this image is located about two degrees south of the large and well-known Orion Nebula (Messier 42), which can be seen at the top edge of the wider view in visible light from the Digitized Sky Survey.
###
The APEX observations used in this image were led by Thomas Stanke (ESO), Tom Megeath (University of Toledo, USA), and Amy Stutz (Max Planck Institute for Astronomy, Heidelberg, Germany). APEX is a collaboration between the Max Planck Institute for Radio Astronomy (MPIfR), the Onsala Space Observatory (OSO) and ESO. Operation of APEX at Chajnantor is entrusted to ESO.
Notes
[1] In German, "Hier ist wahrhaftig ein Loch im Himmel!"
[2] V380 Orionis has a high surface temperature of about 10 000 Kelvin (about the same in degrees Celsius), nearly twice that of our own Sun. Its mass is estimated to be 3.5 times that of the Sun.
More information
The year 2012 marks the 50th anniversary of the founding of the European Southern Observatory (ESO). ESO is the foremost intergovernmental astronomy organisation in Europe and the world's most productive ground-based astronomical observatory by far. It is supported by 15 countries: Austria, Belgium, Brazil, the Czech Republic, Denmark, France, Finland, Germany, Italy, the Netherlands, Portugal, Spain, Sweden, Switzerland and the United Kingdom. ESO carries out an ambitious programme focused on the design, construction and operation of powerful ground-based observing facilities enabling astronomers to make important scientific discoveries. ESO also plays a leading role in promoting and organising cooperation in astronomical research. ESO operates three unique world-class observing sites in Chile: La Silla, Paranal and Chajnantor. At Paranal, ESO operates the Very Large Telescope, the world's most advanced visible-light astronomical observatory and two survey telescopes. VISTA works in the infrared and is the world's largest survey telescope and the VLT Survey Telescope is the largest telescope designed to exclusively survey the skies in visible light. ESO is the European partner of a revolutionary astronomical telescope ALMA, the largest astronomical project in existence. ESO is currently planning the 39-metre European Extremely Large optical/near-infrared Telescope, the E-ELT, which will become "the world's biggest eye on the sky".
Links
* The research into the dark patch in NGC 1999 discussed above is described in a paper by T. Stanke et al., A&A 518, L94 (2010) (http://dx.doi.org/10.1051/0004-6361/201014612), also available as a preprint (http://arxiv.org/abs/1005.2202).
Douglas Pierce-Price
ESO ALMA/APEX Public Information Officer
Garching, Germany
Tel: +49 89 3200 6759
Email: dpiercep@eso.org
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Setting the dark on firePublic release date: 23-Jan-2013 [ | E-mail | Share ]
Contact: Douglas Pierce-Price dpiercep@eso.org 49-893-200-6759 ESO
In space, dense clouds of cosmic gas and dust are the birthplaces of new stars. In visible light, this dust is dark and obscuring, hiding the stars behind it. So much so that, when astronomer William Herschel observed one such cloud in the constellation of Scorpius in 1774, he thought it was a region empty of stars and is said to have exclaimed, "Truly there is a hole in the sky here!" [1]
In order to better understand star formation, astronomers need telescopes that can observe at longer wavelengths, such as the submillimetre range, in which the dark dust grains shine rather than absorb light. APEX, on the Chajnantor Plateau in the Chilean Andes, is the largest single-dish submillimetre-wavelength telescope operating in the southern hemisphere, and is ideal for astronomers studying the birth of stars in this way.
Located in the constellation of Orion (The Hunter), 1500 light-years away from Earth, the Orion Molecular Cloud Complex is the closest region of massive star formation to Earth, and contains a treasury of bright nebulae, dark clouds and young stars. The new image shows just part of this vast complex in visible light, with the APEX observations overlaid in brilliant orange tones that seem to set the dark clouds on fire. Often, the glowing knots from APEX correspond to darker patches in visible light -- the tell-tale sign of a dense cloud of dust that absorbs visible light, but glows at submillimetre wavelengths, and possibly a site of star formation.
The bright patch below of the centre of the image is the nebula NGC 1999. This region -- when seen in visible light -- is what astronomers call a reflection nebula, where the pale blue glow of background starlight is reflected from clouds of dust. The nebula is mainly illuminated by the energetic radiation from the young star V380 Orionis [2] lurking at its heart. In the centre of the nebula is a dark patch, which can be seen even more clearly in a well-known image (http://www.spacetelescope.org/images/opo0010a/) from the NASA/ESA Hubble Space Telescope.
Normally, a dark patch such as this would indicate a dense cloud of cosmic dust, obscuring the stars and nebula behind it. However, in this image we can see that the patch remains strikingly dark, even when the APEX observations are included. Thanks to these APEX observations, combined with infrared observations from other telescopes, astronomers believe that the patch is in fact a hole or cavity in the nebula, excavated by material flowing out of the star V380 Orionis. For once, it truly is a hole in the sky!
The region in this image is located about two degrees south of the large and well-known Orion Nebula (Messier 42), which can be seen at the top edge of the wider view in visible light from the Digitized Sky Survey.
###
The APEX observations used in this image were led by Thomas Stanke (ESO), Tom Megeath (University of Toledo, USA), and Amy Stutz (Max Planck Institute for Astronomy, Heidelberg, Germany). APEX is a collaboration between the Max Planck Institute for Radio Astronomy (MPIfR), the Onsala Space Observatory (OSO) and ESO. Operation of APEX at Chajnantor is entrusted to ESO.
Notes
[1] In German, "Hier ist wahrhaftig ein Loch im Himmel!"
[2] V380 Orionis has a high surface temperature of about 10 000 Kelvin (about the same in degrees Celsius), nearly twice that of our own Sun. Its mass is estimated to be 3.5 times that of the Sun.
More information
The year 2012 marks the 50th anniversary of the founding of the European Southern Observatory (ESO). ESO is the foremost intergovernmental astronomy organisation in Europe and the world's most productive ground-based astronomical observatory by far. It is supported by 15 countries: Austria, Belgium, Brazil, the Czech Republic, Denmark, France, Finland, Germany, Italy, the Netherlands, Portugal, Spain, Sweden, Switzerland and the United Kingdom. ESO carries out an ambitious programme focused on the design, construction and operation of powerful ground-based observing facilities enabling astronomers to make important scientific discoveries. ESO also plays a leading role in promoting and organising cooperation in astronomical research. ESO operates three unique world-class observing sites in Chile: La Silla, Paranal and Chajnantor. At Paranal, ESO operates the Very Large Telescope, the world's most advanced visible-light astronomical observatory and two survey telescopes. VISTA works in the infrared and is the world's largest survey telescope and the VLT Survey Telescope is the largest telescope designed to exclusively survey the skies in visible light. ESO is the European partner of a revolutionary astronomical telescope ALMA, the largest astronomical project in existence. ESO is currently planning the 39-metre European Extremely Large optical/near-infrared Telescope, the E-ELT, which will become "the world's biggest eye on the sky".
Links
* The research into the dark patch in NGC 1999 discussed above is described in a paper by T. Stanke et al., A&A 518, L94 (2010) (http://dx.doi.org/10.1051/0004-6361/201014612), also available as a preprint (http://arxiv.org/abs/1005.2202).
Douglas Pierce-Price
ESO ALMA/APEX Public Information Officer
Garching, Germany
Tel: +49 89 3200 6759
Email: dpiercep@eso.org
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
NEW YORK (AP) ? Sting's daughter Mickey Sumner has signed up to make her off-Broadway debut in Craig Lucas's new comedy "The Lying Lesson."
The Atlantic Theater Company said Tuesday that Sumner, whose credits also include the new Noah Baumbach film "Frances Ha," will star opposite Carol Kane in the comic thriller.
Kane plays a woman who may or may not be legendary screen star Bette Davis and Sumner will portray a woman who tries to discover her true identity.
Previews begin Feb. 20 with an opening set for March 13. Tony Award-nominated director Pam MacKinnon will replace Anna D. Shapiro as the play's director.
Sumner, whose mother is Trudie Styler, made her New York stage debut in a Culture Project workshop of "The Seagull" and is featured in the Showtime series "The Borgias."
One of the reasons that Google’s shares might have popped about 5 percent in after-hours trading is evidence that the company is stabilizing declines in cost-per-click. The closely watched metric is a measurement of how much advertisers are paying on average when consumers actually click through on paid search keywords or on other ads. It declined dramatically throughout 2012, raising concerns that the shift toward searches on smartphones was cannibalizing pricier ads on the non-mobile web. Cost-per-click was up 2 percent quarter-over-quarter, but down 6 percent year-over-year, according to today’s earnings. If you exclude the impact of foreign exchange fluctuations, they were up 1 percent quarter-over-quarter, but down 4 percent year-over-year, according to the earnings call. While the annualized declines don’t look great, they’re far lower than year-over-year declines from the second and third quarter of last year, which were 16 percent and 15 percent respectively. While Google CEO Larry Page and Senior Vice President Nikesh Arora didn’t really explain what helped slow declines in the last quarter, both were optimistic about prices for mobile ads. “We’re in uncharted territory in these things because of the rapid rate of change,” Page said on the earnings call. “The CPCs will improve as these devices improve.” He later elaborated as analysts asked two or three variations on this question (most of which he frankly evaded). “I don’t think this is a long-term problem,” he said. “As I’ve said before, there are a lot of advantages to mobile. You know the location of the user.” Facebook CEO Mark Zuckerberg has said he’s similarly hopeful about mobile ads. The company has been aggressively pushing app install ads and sponsored stories in the mobile news feed throughout the winter. But we won’t know how well these have done until the company reports earnings next week on Jan. 30. At our conference TechCrunch Disrupt back in September, he said on-stage, “I?m really optimistic. It?s more like TV than the Web. The ads we run on mobile perform better than the right-hand ads do on the site.”
SAN FRANCISCO (AP) ? Google eked out slightly higher earnings in the fourth quarter, despite a financial drag caused by the Internet search leader's expansion into device manufacturing and a decline in digital ad prices as more people gaze into the smaller screens of smartphones.
The results announced Tuesday pleased investors, helping to lift Google's stock by 5 percent in extended trading.
More advertising poured into Google during the holiday shopping season, fueling a moneymaking machine that has steadily churned out higher profits since the company went public in 2004. Google's fourth-quarter ad revenue totaled $12.1 billion, a 19 percent increase from the previous year.
Some of that money, though, has been shifting away from personal computers as advertisers try to connect with an expanding audience that relies on smartphones and tablet computers to reach Google's search engine, email and other online services. By some estimates, about one-fourth of the clicks on Google's search ads are now coming from mobile devices.
So far, advertisers have been unwilling to pay as much money to market their wares on mobile devices, largely because the smaller screens leave less room for commercial links and other marketing messages. The trend is one of the reasons that the average price for the ads that Google shows next to its search results has fallen from the previous year in five consecutive quarters, including the final three months of last year.
In a positive sign, though, Google's average ad prices in the most recent quarter dropped by just 6 percent from the same period in 2011. That's the smallest decline during the pricing downturn, raising hopes that Google may be starting to solve the pricing problems posed by the growing usage of mobile devices.
In a conference call Tuesday, Google CEO Larry Page predicted ad prices will gradually rise as the devices become even more sophisticated to unleash new ways to reach potential customers at the times they are most likely to buy something.
"In today's multi-screen world, the opportunities are endless," Page said.
Google earned nearly $2.9 billion, or $8.62 per share, during the fourth quarter. That compared to net income of $2.7 billion, or $8.22 per share, at the same time last year.
If not for the costs of employee stock compensation and certain other accounting items, Google said it would have earned $10.65 per share. On that basis, Google exceeded the average earnings estimate of $10.54 among analysts surveyed by FactSet.
It proved to be a difficult quarter to decipher because of an accounting quirk and the additions of new business lines that muddied the comparisons with the previous year.
For instance, Google Inc. didn't own Motorola Mobility in 2011, having completed its $12.4 billion acquisition of the troubled handset maker eight months ago. What's more, the Google is bringing in more revenue from tablet computers, which it began selling under the Nexus brand during the final half of last year.
Things were further complicated by Google's recent agreement to sell a part of the Motorola Mobility division that makes cable TV boxes. That division is now accounted for as a discontinued operation whose revenue wasn't booked in the latest quarter, even though it will remain a part of Google until the $2.35 billion sale is completed later this year.
Under that equation, revenue surged 36 percent from the previous year to $14.4 billion.
After subtracting advertising expenses, Google's revenue totaled $11.3 billion. That figure was well below the average analyst estimate of $12.1 billion, according to FactSet.
But many of the analyst forecasts included revenue from Motorola Mobility's set-top division, which Google excluded from its breakdown. Had the set-top division been included in Google's accounting, the company's net revenue would have matched analyst estimates.
The performance boosted Google's stock by $35.33 to $738.20 in Tuesday's extended trading.
Google would be doing even better if not for problems at Motorola Mobility, a cellphone pioneer that has been struggling since Apple revolutionized the industry with the release of the iPhone in 2007.
Motorola Mobility suffered an operating loss of $353 million on revenue of $1.5 billion in the fourth quarter
Google has been able to offset the slump in its search advertising prices by selling more video advertising on its YouTube subsidiary and other more graphical forms of marketing. The number of clicks on Google ads has still been rising, too. That's important because the company typically gets paid by the click. In the fourth quarter, Google's total ad clicks rose 24 percent from the previous year.
To gain a foothold in the mobile market, Google bakes its services into its Android software, an operating system that it gives away to makers of smartphones and tablets.
Android is now powers more than 500 million mobile devices worldwide, giving it a wide lead over Apple's software for iPhones and iPads. Through September, Apple had shipped about 370 million iPhones and iPads. Apple Inc., which has morphed from a Google ally to bigger rival in the past five years, is scheduled to release its fourth-quarter results after the stock market closes Wednesday.
Google, which is based in Mountain View, Calif., didn't update how many more Android devices were activated in the fourth quarter..
All Critics (45) | Top Critics (20) | Fresh (44) | Rotten (1)
"Brooklyn Castle" easily checkmates your inner cynic.
Katie Dellamaggiore's lively and affecting documentary introduces us to a cast of characters that's very winning (in both senses of the word).
It's not To Sir, With Love: It's fierce ambition, the channeling of emotion, and hours of drilling.
Enlightening, inspiring and expertly crafted.
An irresistibly uplifting doc.
Castle is suspenseful, funny and, particularly in its depiction of the challenging home lives of some of the kids, moving.
... a powerful and positive story about dedicated teachers helping kids succeed no matter what their circumstances
Like chess, not exactly a high-energy experience but seeing what these kids accomplish, seemingly against all odds is breathtaking all the same.
...provides a corrective to the popular image of American schools as obsessed with sports and popularity, and it makes the strongest possible case for funding after-school activities.
Chess, brilliant young students and great teachers potent mix.
The I.S. 318 team? A delightfully motley, vulnerable, multicultural bunch, whose addiction to chess has allowed them higher aspirations for top high schools and, eventually, college and careers. You will root for them like crazy.
We meet five of the team's members and several of their teachers; by its end, you'll be rooting for them all.
"BROOKLYN CASTLE is a compelling, engaging and inspiring Documentary, featuring Junior High kids that you can relate to. Even if you don't know the game of Chess all too well, it won't stop you from enjoying this pleasant film."
Brooklyn Castle provides a snapshot of indomitable American can-do attitude, and gives one hope.
The admirable Brooklyn Castle transcends its formula to become an optimistic look at extracurricular education and young people.
Great story, well-made, what's not to like?
It's clear that chess isn't just a game; for these students, it can also open doors.
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